Managing organizational design and change Essay

Managing organizational design and change - Essay Example Persons must always come together to form an organization. A workable system and structure set up by more than two people forms an organization. (Fleming, 1989) describes it as a process of identifying and putting together the work to be performed, through definition and delegation of authority and responsibility, while establishing a relationship for the sole duty of ensuring that people work most effectively together in achieving set objectives. With systems and structures an organization is formed. This is by setting up of policies, rules, laws and chain management to run the whole set up structure. When a chain of management is put in place it is tasked with implementation of the set policies and rules. Policies form a critical phase in the running of the company. Leadership also forms a critical part in the running of an organization. With good and well governed leadership an organization is bound to excel and meet its targets and objectives. Lack of leadership and set policies and targets and organization will fail. This is an indication that an organisation is a group of people who have come together to work towards achieving a common goal guided by a given leadership. People with the same ideals, goals, and targets come together to form an organisation. The organisation is therefore tasked with the duty of achieving the set goals and target that have been made by various individuals. The leadership and management structure of any organisation is tasked with the duty of laying up structures and polices which ensures that an organisation is well run and organized. Organizations therefore implement the set policies and rules to ensure that their objectives are met. Organizations are formed to implement the policies and targets set up by the people who run it. Organizations can never be all the same. This is due to the varied nature of objectives of each organization. Depending on its objectives one organization will be

Nucleic acid hybridisation and Nucleic acid probes Essay

Nucleic acid hybridisation and Nucleic acid probes - Essay Example For instance, if a DNA strand with a desired nucleotide sequence is to be detected from a mixture of many other strands, an oligonucleotide containing a few complementary bases to the desired sequence can be prepared and attached to an anchor such as a membrane or a paper. When soaked in a solution having a mixture of many strands, the one, which is complementary to the oligonucleotide, will bind to it through complementary base pairing, also known as â€Å"zippering† (Lodish et al, 2004, p. 11). When double stranded DNA is heated in a dilute salt solution, its two strands separate because of the breakdown of complementary base pairing (melting). This strand separation is called denaturation. The temperature at which the two complementary strands separate is called the melting temperature ‘Tm’, and is affected by the percentage of G.C base pairs, ion concentration of the solution, presence of destabilising compounds like urea, and the pH of the solution (Lodish et al, 2004, p. 105). A particular fragment of DNA or RNA whose nucleotide sequence is complementary to a gene or nucleotide of interest is called a nucleic acid probe. A nucleic acid probe has to be designed in such a way that it hybridises through complementary base pairing to the target DNA or RNA that has to be detected. It should be long enough (about 20 nucleotide long) to pair exclusively to the target nucleotide sequence. Probes are labeled with radioactive tracers, histochemical compounds or fluorescent dyes to enable their detection from a heterogeneous mixture of nucleic acids (Nussbaum et al, 2004, p.41). For instance, 32P labeled probes are developed using polynucleotide kinase that transfers a

HCM367-0801B-01 The Health Care Organization - Phase 2 Discussion Essay

HCM367-0801B-01 The Health Care Organization - Phase 2 Discussion Board - Essay Example of physicians, nurses and para-medics, and our health plan which provides medical and health care to thousands of patients, and group health plans which assist thousands of employees in various firms and their families is witness and testimony to the goodwill Vitruvian enjoys. Our involvement in the medical field makes it obligatory for us to pursue excellence while providing the healing touch. Our principles and policies have been established and nurtured over the years which speak for themselves on the course we have chosen in spite of difficulties and hurdles that came our way. There is no question of any deviation on issues concerning our vision and mission. As has always been the case, we will continue to involve in the best practices, attract the best medical professionals, follow the best ethical and business standards, and provide the most effective care and services to society at large for the mutual benefits of our patients as well as our staff and partners. Medical treatment and practices have existed since the foundation of the world. A great amount of faith and fellowship blended with the line of treatment that Dr Montenegro espoused and demonstrated. It challenged the modern day often misinterpreted belief that the best medical treatment can be found only in technologically advanced facilities. Many times these advanced facilities are resorted to even when simpler ones would have sufficed. Nevertheless, the scope to harness the best in technology does exist. As is the case in the medical fraternity the world over, and keeping in view the tremendous potential in the medical technology of the day, it is imperative that we have access to the best medical treatment and facilities for the mutual benefit of our patients and our organization, as and when required. The guiding principles enshrined in the Memorandum of Understanding (MoU) will continue to be operational in the future as it is so now. Any changes or modifications required in the days ahead